INTRODUCTION: Stress is defined as a state of disturbed balance in the physiological, psychological and social functioning of an individual, caused by perceived threats. Continuous exposure to stress in the workplace can lead to emotional exhaustion and professional burnout. Nurses and technicians, especially in emergency medicine, face numerous sources of stress every day, which can threaten their efficiency and quality of health care. OBJECTIVE: The aim of this research work was to examine the consequences of stress and the level of professional burnout of nurses/technicians employed in emergency medicine (while controlling for gender, age, work unit system, level of education and seniority). Personal challenges and experiences of employees in the field of emergency medicine were separately covered by open-end questions. METHOD: The research was conducted on a convenient sample of nurses/technicians employed in emergency medicine in the period from May 1, 2023 to July 1, 2023. A total of 285 nurses/technicians employed in the field of emergency medicine in the Republic of Croatia participated. The research was conducted through an online structured questionnaire. RESULTS: The participants of this study, as consequences of stress at work, mostly reported insomnia, headaches and indigestion due to the demands of the job. Analyzing the results obtained from the professional burnout questionnaire, the majority of the participants of this research cite special warning signs (33.7%) or a serious level of burnout (24.9%), which indicates the demanding and stressful nature of work in the field of emergency medicine. The incidence of occupational burnout differed with regard to gender and work unit system. CONCLUSION: Symptoms of professional burnout are present to a large extent in nurses/technicians employed in the field of emergency medical care. Also, there are differences in the incidence of professional burnout with regard to some sociodemographic characteristics of the participants.