Quality of life is a term for which there is no universally accepted definition, but each science defines it in its own way. Geographically, it is defined as a space that is suitable for life and which fulfills basic human needs. The main aim of the thesis is to examine the quality of life in three selected Croat-Roma settlements of Međimurje County (Pribislavec, Orehovica, Mala Subotica). The settlements where the share of the Roma national minority in the total population is the largest were selected for the purposes of the research. In order to examine the quality of life, a survey was conducted. Thus, the major Croatian population was asked how satisfied they were with the natural environment, social relations, safety and the risk of exposure to crime in their place of residence. Survey research revealed that the quality of life in Croat-Roma settlements is impaired and that the Croat and Roma population are in poor social relations. One of the main problems that arises is the spatial separation and marginal position of members of the Roma national minority. Such spatial separation of the Roma national minority has a harmful effect on the economic and sociocultural factors of their lives. Four hypotheses are set in the paper. H1 (Croatian population in Croat-Roma settlements is dissatisfied with the quality of life) and H3 (Croatian population does not feel safe in Croat-Roma settlements) were not confirmed, while H2 (The population in the settlement of Pribislavec is the least satisfied with the quality of life) and H4 (The population in the settlement of Orehovica is the least dissatisfied with the influence of Roma national minority on the natural environment) were confirmed.