The stigma associated with mental disorders is one of the many obstacles to providing quality mental healthcare, treatment of somatic disorders, and better quality of life for patients. Stigmatization is one of the biggest problems that a person encounters. When a person becomes ill, he or she not only has to deal with the illness, but also with a number of other problems due to the serious nature of the problem and it represents a major obstacle in the rehabilitation and reintegration of the patient. The stigma leads to reduced life satisfaction and self-esteem, as well as addictions, depression and suicidality. A high-quality therapeutic relationship achieved through education should be implemented across all departments, not only in the psychiatric department, as such an approach facilitates proper treatment of the patient, thus ensuring the safety of patients. This paper shows how people with mental health disorders deal with the stigma in their environment and how medical nurses treat patients with mental health disorders with the aim of planning education for the acceptance of patients with mental health disorders as equal persons along with their rights. In addition to the burden of their own illness, people with mental health disorders endeavor to deal with the stigma that society has towards them on a daily basis. The stigma leads to prejudices and, eventually discrimination and rejection. Patients find the greatest support within their families. What is most often evident to family, friends, psychiatrists, psychologists and others is the shame patients have regarding their illness, often hiding it. It is visible in their daily communicationwhen they open up and talk about their condition. The paper also touches on the topic of negative comments, who makes such comments and which negative comments most affect patients. People with mental disorders are aware that society stigmatizes them. Educating and sensitizing society is the basis of combating the mentioned stigmatization.