Mobbing and burnout syndrome are a significant problem not only for individual healthcare professionals, but also for the overall healthcare system. Due to its complex nature, the issue of mobbing in this paper is sought to be developed by defining mobbing and reviewing its prevalence rates, manifestations and stages through which it develops, but also basic methods and instruments for measuring it, as well as environmental and personal risk factors and effects on the health and professional work of employees exposed to it. Burnout syndrome is considered through various theoretical approaches that interpret it as a process, state or a combination of them, and from which some of its more common definitions are derived. The high prevalence of burnout among healthcare professionals is explained by the interaction of certain individual characteristics of employees and situational factors of work / work organization, where burnout manifests itself in the form of certain signs and / or symptoms and possible consequences. The main tool for measuring burnout among healthcare professionals, the Maslach Burnout Inventory (Human Services Survey) can be used to identify different burnout profiles. The positive connection between the exposure of healthcare professionals to mobbing and their experience of burnout in the workplace is explained through theoretical models of stress, where available knowledge about mobbing, burnout and the mechanisms of their connection enable appropriate implementation of prevention, with interventions integrated to address the critical characteristics of employees and / or their work / work organization.