Introduction: Hepatitis C can also be called a liver infection. HCV is a single-stranded envelope RNA virus. Following the main phylogenetic tree today, we distinguish six HCV genotypes (HCV1, HCV2, HCV3...). The most common genotype in the world and in Croatia is genotype 1. Genotype 1 accounts for almost 49.1% of infections. Hepatitis C is transmitted from person to person by infected blood. The most common route of transmission is parenteral (transfusion, use of contaminated equipment during IV drug use, surgery, tattooing), in addition, it can be transmitted sexually and vertically - from mother to child. The incubation time lasts 6 to 7 weeks. Hepatitis C is an important public health problem because as many as 80% of infections remain clinically unrecognizable. Cirrhosis of the liver is the most common consequence of the silent impact of hepatitis C and develops in 20% of patients. A small number of people, 1-5% develop hepatocellular carcinoma. In 2011, the first direct-acting antiviral drugs were introduced. Studies have shown that with DAA therapy, cure is recognized in 95% of cases. Purpose: To show nurses rolein care for patients with hepatitis C Discussion: In the process of health care carried out in a patient suffering from an acute hepatitis C infection, emphasis is placed on the observation of his activity, cardiovascular system, metabolism, appearance of the skin and visible mucous membranes. In the health care of patients with chronic hepatitis virus, nursing interventions are focused on education and supportive work with the patient. Conclusion: The nursing bachelor assesses the patient's condition and determines his needs. Data collection and condition assessment is a database that assists the nurse in determining the nursing diagnoses present. After the nursing diagnoses are set, the bachelor of nursing plans and implements interventions that will achieve the desired goal. The desired goal is always aimed primarily at improving the general condition and quality of life of each patient.