The incidence of acute pancreatitis in the world varies from 5 to 80 cases per 100,000 inhabitants while the incidence of acute pancreatitis in European countries is from 30 to 50 cases per 100,000 inhabitants. Acute pancreatitis is an inflammation of the pancreas caused by the release of pancreatic enzymes from the pancreas into the surrounding tissue. The etiology is not completely known, but common causes include biliary tract diseases, alcohol, gallstones, medication, and hormone secretion disorders. The clinical picture is dominated by severe pain most often localized in the epigastrium which later moves to the upper left quadrant and back. The pain usually occurs a few hours after a fatty meal or heavy alcohol consumption. The diagnosis is made on the basis of clinical images, laboratory tests, ECG, X-ray of the heart and lungs, a native image of the abdomen and a test strip for the determination of trypsinogen in urine. Treatment is usually conservative-analgesics, the gastric contents are pumped with a nasogastric tube for the first 48-72 hours. Surgical treatment is undertaken only in case of complications. Mortality in acute pancreatitis depends on the degree of inflammation, more precisely the involvement of the pancreas with inflammation. In the mild form of acute pancreatitis it is less than 5%, while in the severe form it varies from 10-50%. In the treatment of acute pancreatitis, we place emphasis on a multidisciplinary approach. An important role in the teams is played by the nurse who observes the patient's condition, performs and participates in diagnostic and therapeutic procedures, provides health care, provides psychological support to the patient and conducts education.