INTRODUCTION: Flu or Influenza is a disease that occurs very suddenly and manifests itself with high temperature, headache, fatigue and muscle pain. We define it as an infectious disease of the respiratory system caused by influenza viruses. It occurs periodically, most often in winter, and is easily transmitted. It is considered the only pandemic disease because it is not locally restricted and affects larger geographical areas. OBJECTIVE: To show the role of Bachelor of nursing in preventing the emergence and dissemination of influence in the General Hospital of Zadar. DISCUSSION: The role of bachelor in preventing the spread of a flu is the implementation of educational interventions in daily work before the flu season through primary and secondary prevention. It is of the utmost importance that all staff have available treatment and care instructions, and be familiar with how preventive measures are taken to spread the flu. The Commission for the Control of Hospital Infections other than the forwarding of information to employees during the epidemic of seasonal influenza in the general population, temporarily restricts visits to patients in the departments, except for family members of the patient. CONCLUSION: This paper gives an insight into the etiology of influenza-induced infections, existing standards, guidelines and prevention measures in the General Hospital of Zadar, where the emphasis is placed on the work of Bachelors of nursing. The Bachelor of nursing should have knowledge of the etiology of infections caused by influenza viruses and be familiar with the measures and guidelines for preventing the spread of infection in order to timely observe and take all prescribed measures of isolation.