This paper presents the portrayal and comparison of the sorceresses that appear in the works of certain ancient Greek writers. Circe and her cousin Medea are the archetypes of ancient Greek mythical sorceresses of divine origins. The figure of Circe as the first literary sorceress is found in Homer's work, and alongside her we find two more sorceresses, nymph Calypso and Zeus's beautiful daughter Helene. The most well known sorceress Medea is portrayed in the work of three authors (Apollonius Rhodius, Diodorus of Sicily (Siculus), Euripides), each of them bringing an important turning point in her life. Euripides presents two more mythical sorceresses, the mortal Andromache in the tragedy of the same name and Phaedra in the tragedy Hippolytus. The portrayal of Deianira is presented by Diodorus Siculus in his historical work Bibliotheca historica and by Sophocles in his tragedy Women of Trachis. The Hellenistic poet Theocritus, the orators Demosthenes and Antiphon bring portrayals of imagined or real women who were considered to be sorceresses. Through their presentations we see their reasons for using magic, the way of performing magic, and the results of using various magic substances such as herbs, ointments and potions.