The paper presents the strategy human resource management with emphasis on the Lika-senj County. Human resources are a significant factor of the development of modern economies and the strategic management of human resources is a key element of success. The appropriate management of human resources contributes to the innovation and the achievement of development goals high on the territory of Lika-senj County. Lika-senj County infrastructure is developed, has rich natural resources and the historical and cultural heritage. The introduction of the strategy for the development of human resources will be achieved a reduction of the existing developmental problems such as reducing the number of employees, the lower the average salary paid per employee in the County, compared with the average of the Republic of Croatia, the reduced supply of labour in relation to the the demand. Requalification is needed for part of the working population in accordance with the needs of the economy as well as to foster a more favourable socio-economic conditions of life, such as housing, health care, the care of children, to reduce the cultural and recreational migratory movement of the population.