More and more modern companies are faced with the problem of the complexity of human resource management. Namely, although it is not at all easy to manage all other resources, they are still humanly specific and that is why great importance is attached to ways of managing them. Therefore, in this paper, the main goal will be to research the characteristics and importance of the human resources management process, as well as the description of its activities. Also, in addition to the theoretical, the next goal will be the practical one, for example the goal of presenting the way of managing human resources in world-famous hotel companies. The paper presents five selected multinational hotel companies from different parts of the world, and emphasis will be placed on their human resource management processes. Based on the obtained results, it could be concluded that the selected hotel companies are leading in the world, which is due to many factors, one of which is the quality management of human resources. Namely, many years of commitment, work and effort of the companies and their employees have resulted in successful business results and a great competitive advantage. However, it is definitely necessary to emphasize that there is always place for improvements and all these organizations should strive for the same.