Breast, mamma is an apocrine gland characteristic of the female sex, with the function of producing milk. The structure and functional state of the breast change throughout life. Breast disease can occur between age of 25 and 80, the incidence and mortality increase with age. Cancer is a complex disorder in the cellular genome that leads to numerous changes in cellular function. Breast cancer is the most common type of cancer amongst women, and the most common malignant cause of death in women in more than 90% of countries in the world and also one of the most common causes of death in women in general. The incidence rate of breast cancer in women is 100% higher than in men, it affects only 1-2% of men. The etiology of the disease itself is complex, the disease is influenced by a number of factors related to lifestyle, reproductive behavior, endocrine and genetic factors. In Croatia, one in 9.5 women develops breast cancer during their lifetime, and in developed Western European countries and the USA, one in eight women develops it during their lifetime. According to the latest research conducted for Zadar County in 2018, the number of deaths from malignant breast neoplasms is a total of 31 people, of which 29 women and 2 men. The incidence of malignant breast neoplasms in women in 2016 was 28.8%, according to the other incidence of malignant diseas. „The first step in the diagnosis of tumor changes in the breast are history, inspection and palpation, and self-examination or clinical examination of the breast. The treatment of breast cancer depends on the stage of the disease and the type of tumor. Mortality from breast cancer has been declining since 1991 as a result of early detection and more effective treatment “. The aim of this research is to show the occurrence of cancer in the Zadar County and the outcome of the disease. Data were collected from the Annals of the Croatian Institute of Public Health in Zadar County.