Introduction: Patients who are suffering from chronic kidney failure and are on dialysis treatment have a high risk of developing cardiovascular incidences, and hypertension is the most important risk factor. Objective: The research goal is to determine the degree of regulation and compare the value of arterial blood pressure in patients on hemodialysis with patients on peritoneal dialysis. Methods and respondents: The research is conducted retrospectively during 2017 at the General Hospital of Zadar. Methods of collecting, analyzing and synthesizing data have been used. Data were collected from the hospital information system. The study included 47 patients (30 patients on hemodialysis and 17 patients on peritoneal dialysis). Subjects were randomly selected, regardless of age, sex, comorbidity, and ordinated therapy. Results: On hemodialysis, 76.67% of patients has hypertension and 94.11% of patients on peritoneal dialysis. In the study, the difference in systolic blood pressure in patients on hemodialysis compared to patients on peritoneal is not statistically significant (t = 0.64, df = 233, p = 1.97, p> 0.05) and the values for diastolic blood pressure are also not statistically significant (t = 1.26, df = 233, p = 1.97, p> 0.05). Furthermore, the difference is not statistically significant in patients on hemodialysis due to age (t = 1.09, df = 148, p = 1.98, p> 0.05) In addition, the data obtained suggest that hemodialysis patients with 3 or more antihypertensive drugs have poorer regulated blood pressure than those with less ordinated antihypertensives (t = 7.45, df = 148, p = 1.98 and p <0.05). Blood pressure control has 46.67% of patients on hemodialysis and 47.06% on peritoneal dialysis. Conclusion: Despite the advancement of medicine and the availability of various medicines and methods of blood pressure control, it is a challenge for all healthcare professionals and patients suffering from chronic renal insufficiency if we take in consideration possible consequences.