Acute inflammation of the appendix is one of the most common modern surgical emergencies that can occur in both sexes and in people of all ages. The treatment of this condition mainly involves the use of laparoscopic appendectomy, a minimally invasive surgical procedure that removes the inflamed appendix from patients. Despite significant advances in technology, the diagnostic procedure is still very challenging and involves the application of several techniques to determine the correct diagnosis, and includes clinical examination, laboratory and radiological treatment of the patient. The appearance of complications due to the lack of timely treatment or as part of the postoperative process is also a possibility that in some cases can result in a fatal outcome for the patient. The aim of this research is to present basic data related to acute inflammation of the appendix, with special emphasis on the diagnosis and treatment of acute inflammation of appendix in children. The purpose of the research is to compare the data on the clinical picture and laboratory findings with the operative findings and to examine the degree of agreement in the specified parameters. The research includes a retrospective analysis of data collected through the hospital information system of Zadar General Hospital. The data includes information on 56 patients who, in the period from 01.01.2021. until 31.12.2021, undergo treatment for acute inflammation of the appendix. Collected data include gender and age of patients, form of diagnosis, total number of days of hospitalization and value of laboratory findings. The research covers children aged 4 to 18 years. The data are presented with frequencies and percentages through graphical representations in the form of tables and diagrams.