Down syndrome is the most common genetic disorder that occurs due to changes in the nucleus of almost every cell in the body. It is one of the most common genetic disorders in the population carrying with it a number of developmental problems as well as problems associated with adapting to the social environment. In addition to developmental and social problems, children and parents have to struggle with the state legal system which does not always provide quality support or the possibility for the children to realize their potential. Although the school system, in like manner, is not well adjusted to kids with Down syndrome, examples of children that have been observed thus far do provide hope of change. The paper is divided into two parts; the theoretical part which contains collected knowledge of the syndrome, and the empirical part, which gathers data obtained on the basis of observations of three children with Down syndrome and interviews with their parents and teachers. A few aspects were taken into account; psychomotor development and health issues, social adjustment, adjustment to school as well as the course and structure of the teaching process. A review of the data obtained leads to the conclusion that children observed in this study do indeed have great potential to succeed in maximally developing their skills if they are provided with adequate treatment where they would be treated as children with potential for great success which indeed they are.