The most common diseases of the biliary system are cholelithiasis and choledocholithiasis. Cholelithiasis is a disease of the gallbladder, which affects women in particular. It appears in 10-20% of the world's population after the age of forty. Bile serves as an emulsifier for fats and oil-soluble vitamins in the digestive tract. After the cessation of bile secretion, there may be difficulties in their absorption. This condition can occur due to genetic predisposition or improper diet. Gallstones are divided into cholesterol stones (80%) and pigment stones (20%). While the stones are small, they do not pose a big problem, they can even be extracted from the body through the bile ducts and intestines. However, if the stone becomes too large, it can get stuck in the bile duct and the patient gets an attack of severe pain with nausea and vomiting. The best method for diagnosing gallstones is ultrasound, although there are a number of other tests. When treating cholelithiasis, there are several options: expectant attitude, surgical approach and non-surgical therapy. Laparoscopic cholecystectomy is considered the gold standard in the treatment of gallstones and has a number of advantages over classic cholecystectomy, while the non-surgical approach is mainly used in people who have contraindications for the procedure or who refuse it. A healthy lifestyle and proper nutrition are a key factor in preventing the formation of gallstones, while refusing treatment and not treating it can lead to serious complications. Before surgery, the nurse/technician is responsible for the mental and physical preparation of the patient. After the operation, the nurse/technician participates in the patient's recovery. Their task is monitoring the patient's vital functions, dressing the surgical wound, controlling the drainage and drainage content (in the case of classic cholecystectomy), helping the patient get up. It is important for the nurse/technician to notice postoperative difficulties and complications that may occur in the patient. She also makes nursing diagnoses and evaluates them in order to provide the patient with the best possible health care. When the patient is discharged from the hospital, it is extremely important for the nurse to explain to the patient and his family members the rules and importance of the bile diet that the patient must adhere to, the way and type of consumption of certain foods and activities that are desirable for implementation. She must be educated and ready to answer every question asked by the patient.