Autonomy is a key foundation for the professionalization of the field of activity of subject teachers as members of the profession of the educational system. It is necessary to investigate the new curricular reform, according the School for Life project, in order to get an idea of whether the autonomy of subject teachers has necessarily increased, which novelties the project has brought with it, which is precisely the purpose of this paper. In order to collect data on personal experiences and experiences of subject teachers, the method of semi-structured interview was used. 8 out of a total of 11 subject teachers from one primary school participated. The primary school has 8 classes per 1 class of each class, a total of about 90 students. For the purpose of data collection, the method of working on documentation and analysis of documentation was used: National Framework Curriculum (2011), Croatian National Education Standard: Curriculum (2006), and curricula of all subject subjects from the School for Life project website, as the official changes introduced by the project in the curriculum would be noticed. The obtained data from the work on the documentation provide insight into the official changes in the educational work of the subject teachers and curricula, while the data collected from the interviews provide insight into the personal experiences and experiences of the subject teachers. The obtained results of both analyzes showed some formal and terminological changes, and some changes in the practical work of subject teachers, which include increasing autonomy in choosing the method and form of work, greater awareness of the use of ICT in the work of some changes in student evaluation.