INTRODUCTION: Urinary tract infections related to catheter use are frequently encountered in healthcare environments. The majority of these infections are observed in intensive care units. The factors contributing to these infections can be either modifiable or unmodifiable. OBJECTIVE: To outline and clarify the responsibilities of nurses in preventing urinary infections linked to urinary catheters. DISCUSSION: Among the modifiable factors are continuous catheterization, lack of adherence to aseptic techniques during catheter insertion and maintenance. Nonmodifiable factors include female sex, age younger than 50 years, and serious underlying diseases. Proper procedure when inserting a permanent catheter (Foley catheter) requires a thorough assessment, consideration of alternative treatments, and insertion of the catheter only when necessary. The majority of infections happen when catheters are routinely employed in intensive care units without proper justification. The determination regarding the kind, dimension, and intention behind catheterization is within the domain of the physician. The introduction of a urinary catheter in females typically necessitates the teamwork of two nurses or technicians and must be executed under stringent aseptic conditions. Aseptic precautions should be implemented during catheter and bag handling to avert infections. In the event of complications arising during or after catheter insertion, it is the nurse's responsibility to inform the doctor. All procedures carried out should be documented in the nursing records. CONCLUSION; Nurse-led interventions have demonstrated their effectiveness in reducing the duration of catheterization and lowering infection rates, resulting in improved overall patient well-being and reduced hospital costs.