Slavonski Brod is the regional center and the seat of Brod-Posavina County, whose development is based on a favorable natural basis and geostrategic position. Furthermore, in addition to the geostrategic position, the accelerated urban development of the city is due to the change of functional direction from the trade and craft function to a distinct industrial direction of the city. The positive repercussions of industrialization were reflected in all spheres of life in the city, and most of all in the positive demographic trends. On the other hand, the collapse of the industry had an equal effect on the modern development of the city with an emphasis on extremely declining demographic trends marked by a high emigration rate. The collected data refer to the level of the Slavonski Brod settlement. Using numerous methods, with an emphasis on the analysis of archival material and relevant literature sources, the urban development and transformations of the city encouraged by pronounced industrialization were analyzed. Through the set goals, they tried to explain the causes and consequences of spatial changes in the urban area of the city and analyze the impact of industry on urban transformation. The results of the work based on confirmed hypotheses indicate a significant impact of industry on spatial change and urban expansion of the city as it is today. The continuous development and expansion of industrial enterprises directly affected the employment of residents, which resulted in a marked increase in population and the consequent expansion of urban settlements to the periphery. The construction of workers' settlements along with the reconstruction of the city after the bombing, are the best example of urban transformations in the spatial development of Slavonski Brod.