Goal: To examine which are the most common risk factors that affect the outcome of the disease of patients with Covid-19 in Zadar General Hospital, to examine the outcomes of the treatments of patients, and to check whether there is a statistically significant difference regarding the clinical picture and the outcome of the disease between patients and lder than 65, and between mail and female patinents. Materials and methods: The research was conducted retrospectively by looking at the written database (patients' disease histories) of the Zadar General Hospital. Data from a total of 153 participants were included in the research, of which 63 were female participants during the period of 18.03.2020.-31.10.2020. Results: Of the 153 participants, 41.2% were women and 58.8% were men. The average age of the participants was M=64.37 (SD=16.07). The most common risk factor that affects the outcome of the disease of patients with Covid-19 in Zadar General Hospital is arterial hypertension, while the rarest was immunological disturbance. The largest number of patients had a moderate clinical picture, while of the smallest number of patients had a mild clinical picture. There was a statistically significant difference between men and women in the clinical picture, while there was no statistically significant difference between the sexes in the outcome of the disease. A statistically significant diffrence in the clinical picture and the outcome of the disease was found between the participants younger and those older than 65. Conclusion:The results of our investigation showed that older age, hypertension and diabetes were the most frequent risk factors of disease progression and death outcome of Covid-19.