Title Upotreba anestetika u uvjetima elektivne elektrokardioverzije
Title (english) Use of anesthetics in conditions of elective cardioversion
Author Bernarda Markov
Mentor Tatjana Šimurina (mentor)
Committee member Boris Dželalija (predsjednik povjerenstva)
Committee member Tatjana Šimurina (član povjerenstva)
Committee member Marijana Matek Sarić (član povjerenstva)
Granter University of Zadar (Department of Health Studies) Zadar
Defense date and country 2022-09-16, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Nursing
Abstract UVOD: Srčane aritmije su abnormalnosti ili poremećaji u normalnoj aktivaciji ili otkucajima srčanog miokarda. Ozbiljnost srčanih aritmija ovisi o prisutnosti ili odsutnosti strukturalne bolesti srca. Elektrokardioverzija (eng. electrical cardioversion - EC) srčanih aritmija je često izvođen, standardni postupak za bolesnike u dobrom kliničkom stanju. Kardioverzija se može učiniti kao hitan zahvat ako aritmija šteti hemodinamici i stoga je opasna po život, ali se može učiniti i elektivno. Cilj ovog rada je bio ispitati sigurnost, učinkovitost i nuspojave određenih anestetika koji se koriste za sedaciju i analgeziju u postupcima elektivne elektrokardioverzije u koronarnoj jedinici u Općoj bolnici Šibensko-kninske županije. Istraživanje je obuhvatilo 52 bolesnika, od kojih je 29 (56 %) muškaraca i 23 (44 %) žene. Obzirom na srčani ritam, fibrilaciju atrija prije konverzije imalo je 49 (94,2 %) bolesnika. Uspješna kardioverzija bila je kod 47 (91,4 %) bolesnika. Medijan trajanja anestezije je 10 minuta (interkvartilnog raspona od 10 do 12 minuta) u rasponu od najmanje 8 do najviše 17 minuta. Uredno „buđenje“ (oporavak) bilježi se kod 43 (82,7 %) bolesnika. Propofol kao izbor lijeka za sedaciju dobilo je 17 (33 %) bolesnika, hypnomidate (etomidate) njih 13 (25 %), kombinaciju propofol i lidokain njih 11 (21 %), kombinaciju hypnomidate i midazolam (dormicum) 7 (14 %) bolesnika, a 4 (8 %) bolesnika kao lijek za sedaciju dobili su kombinaciju opioida fentanyla i propofol. Lijek za „buđenje“ dobilo je 9 (18 %) bolesnika, i to 3 / 9 (33 %) nalokson, a 6 / 9 (67 %) bolesnika anexate. Pretraživanjem znanstvenih baza podataka, portala i akademskih internetskih stranica (Pubmed, Researchgate, Google Schoolar, Embase, Hrčak) pronađeni su članci u kojima se opisuje primjena sedativa i analgetika tijekom provođenja elektrokardioverzije koji su pokazali rezultate slične našima. Naime, najčešće primijenjen lijek je bio propofol, a i ostali lijekovi koje smo rabili su pokazali učinkovitost i sigurnost primjene za bolesnika. Nakon postupka elektrokardioverzije bolesnici su imali značajno niži krvni tlak i frekvenciju srca u odnosu na početne vrijednosti prije intervencije, dok se zasićenost krvi kisikom nije mijenjala. Kod jedne trećine bolesnika lijek izbora za sedaciju je bio propofol. Lijek za konverziju radi oporavka nakon sedacije zahtijevalo je 9 (18 %) bolesnika.
Abstract (english) INTRODUCTION: Cardiac arrhythmias are abnormalities or disturbances in the normal activation or beating of the heart myocardium. The severity of cardiac arrhythmias depends on the presence or absence of structural heart disease. Electrocardioversion (eng. electrical cardioversion - EC) of cardiac arrhythmias is a frequently performed, standard procedure for patients in good clinical condition. Cardioversion can be done as an emergency procedure if the arrhythmia harms hemodynamics and is therefore life-threatening, but it can also be done electively.To determine the safety, effectiveness and side effects of certain anesthetics used for sedation and analgesia in elective electrocardioversion procedures in the coronary unit at the General Hospital of Šibenik-Knin County.The research included 52 patients, of whom 29 (56%) were men and 23 (44%) were women. Regarding heart rhythm, 49 (94.2%) patients had atrial fibrillation before conversion. Cardioversion was successful in 47 (91.4%) patients. The median duration of anesthesia is 10 minutes (interquartile range from 10 to 12 minutes) ranging from a minimum of 8 to a maximum of 17 minutes. Regular awakening was noted in 43 (82.7%) patients. Propofol as the drug of choice for sedation was given to 17 (33 %) patients, 13 (25 %) to hypnomid, 11 (21 %) to a combination of propofol and lidocaine, 7 (14 %) to a combination of hypnomid and dormicum, and 4 (8 %) ) patients were given Fentanyl and Propofol as a sedation drug. 9 (18 %) patients received the drug for awakening, namely 3/9 (33 %) naloxone, and 6/9 (67 %) patients received anexate. A search of scientific databases, portals and academic websites (Pubmed, Researchgate, Google Schoolar, Embase, Hrčak) found papers describing the use of sedatives and analgesics during electrocardioversion, which showed similar results. Namely, the most commonly used drug was propofol, and the other drugs also showed effectiveness and safety of use. After the electrocardioversion procedure, the patients had significantly lower blood pressure and heart rate, while blood oxygen saturation did not change. In one third of patients, the drug of choice for sedation was Propofol. 18% of patients required the drug for awakening.
Keywords
aritmije
elektrokardioverzija
sedacija
analgezija
Keywords (english)
arrhythmias
electrocardioversion
sedation
analgesia
Language croatian
URN:NBN urn:nbn:hr:162:734316
Study programme Title: Nursing Study programme type: university Study level: graduate Academic / professional title: Magistar/magistra sestrinstva (Magistar/magistra sestrinstva)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2022-11-04 14:25:48