The name "schizophrenia" was introduced by Swiss psychiatrist Eugen Bleuler. Schizophrenia is recognized by the symptoms of illness, especially acute when patients experience and evaluate reality differently and can not associate their thoughts, retreat into themselves and sleep less. After the acute phase, the intensity of emotion, concentration ability and reduced tolerance to daily loads are reduced. It affects 1,5 to 2 percent of the population, especially younger. Acute schizophrenia occurs several times during life and reduces the patient's effectiveness . The study points to the complexity of health care of a patient with schizophrenia. We are an important part of the psychiatric team. The most important tools in the care of patients with schizophrenia are: knowledge of symptoms of schizophrenia, communication between nurses and patients, experience and skills in team work. The most important in the work with the patient with schizophrenia is the communication and take the principles of health care (reducing or eliminating physical symptoms, achieving behavior, recognizing side effects and complications of psychodrugs, and emergency symptoms). Due to health care monitoring, it is important to conduct health care through the health care proces. The care of patient with schizophrenia is complex and demanding. We conduct nursing anamnesis, nursing diagnosis (through data collection and objective observation of patients), nursing intervention (creating confidence, motivating, carrying out intensive care, encouraging, helping with personal hygiene and nutrition, supervising and controlling, calming the patient) and we evaluate the done .